Imipramine
In stock
75mg · 50mg · 25mg
from A$51.19
In brief
Imipramine hydrochloride, a tricyclic antidepressant, carries the brand name Tofranil on the Australian market. Healthdirect lists two uses for Tofranil: major depression, and bed-wetting at night in children aged 5 or older when an organic cause has been excluded.
A tricyclic antidepressant with a second use in childhood enuresis
Imipramine hydrochloride belongs to the tricyclic group of antidepressants, as the Tofranil CMI on myDr explains. The healthdirect page for Tofranil names major depression as one use and night-time bed-wetting in children from 5 years of age as the other, provided organic causes have been ruled out.
This listing shows imipramine 25 mg, 50 mg and 75 mg. It does not name the manufacturer of the product supplied, so check the label on the pack you receive and confirm with your prescriber or pharmacist that it matches your prescription.
Imipramine 50 mg: 30 units or 90 units
Compare packs of the same strength. These examples are for 50 mg and are calculated from the listed prices at the shop’s Australian-dollar rate on 9 October 2026, before delivery or other checkout charges.
| Strength | Pack size | Pack price | Price per unit |
|---|---|---|---|
| 50 mg | 30 | A$64.65 | A$2.15 |
| 50 mg | 90 | A$135.06 | A$1.50 |
The 90-unit pack works out roughly 30.4% cheaper per unit than the 30-unit pack.
A lower price per unit means a larger upfront payment. Choose only the quantity and strength appropriate to your prescription, and check the expiry date. Prices can change, so confirm the current pack price before ordering.
Tofranil registration in Australia covers 10 mg and 25 mg tablets
Amdipharm Mercury (Australia) Pty Ltd supplies Tofranil here, and healthdirect records it as sugar-coated tablets in two strengths, 10 mg and 25 mg. It is a Schedule 4 Prescription Only Medicine, and healthdirect listed it as subsidised under the PBS as of 1 October 2026. In other words, the 50 mg and 75 mg choices on this page have no Australian registration under the Tofranil name.
Tofranil and a wait of up to 4 to 6 weeks for improvement
The Tofranil CMI states that a noticeable improvement may take up to 4 to 6 weeks to arrive.
Reasons the CMI gives for not taking Tofranil at all
Tofranil is not to be used by anyone allergic to imipramine or to another tricyclic antidepressant, by people currently on an MAO inhibitor, or during recovery from a recent heart attack. After an MAO inhibitor is stopped, two weeks need to pass before imipramine can be started.
Mood, eyes, bladder, heart and daily activities: Tofranil cautions
The CMI warns that suicidal thoughts may occur, with younger people at particular risk, and asks that a doctor be contacted straight away if they do. Do not stop the medicine without first speaking with your doctor. Extra care is needed for people with glaucoma, trouble passing urine, seizures or a heart condition. Alcohol should be avoided, and you should not drive until you have found out how Tofranil affects you. Healthdirect adds that people over 65 face particular risks worth discussing with a doctor, and that advice from a doctor or pharmacist is needed in pregnancy.
Sleepiness, constipation and other Tofranil side effects, plus interactions
Side effects often reported with Tofranil include drowsiness, dizziness, dry mouth, constipation, weight gain, sexual dysfunction and blurred vision. Listed among the serious effects are allergic reactions, a heartbeat that becomes irregular, severe confusion, and movements a person cannot control. Medicines and products the CMI flags for possible interactions are MAO inhibitors, blood pressure medicines, SSRIs, anticonvulsants, warfarin, certain cold remedies and nicotine products.
Storing Tofranil below 30 °C in a dry place
According to healthdirect, Tofranil should be stored below 30 °C and kept away from moisture. Follow the storage directions on the pack you receive.
Delivery across Australia
Standard delivery: 14–22 days. Express tracked delivery: 7–14 days, with the tracking number sent by email. These are estimated delivery times, not guaranteed arrival dates.
Australian cities and delivery information
The Australian delivery options above apply to the destinations below. A city listing does not indicate a physical pharmacy branch or local stock.
| City | State or territory |
|---|---|
| Sydney | New South Wales |
| Melbourne | Victoria |
| Brisbane | Queensland |
| Perth | Western Australia |
| Adelaide | South Australia |
| Hobart | Tasmania |
| Gold Coast | Queensland |
| Canberra | Australian Capital Territory |
| Cairns | Queensland |
| Central Coast | New South Wales |
| Townsville | Queensland |
| Darwin | Northern Territory |
| Newcastle | New South Wales |
| Geelong | Victoria |
| Gladstone | Queensland |
| Port Macquarie | New South Wales |
| Bathurst | New South Wales |
| Forbes | New South Wales |
| Geraldton | Western Australia |
| Goulburn | New South Wales |