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Imipramine

Imipramine
In stock
75mg · 50mg · 25mg
from A$51.19
Strength
Pack size — the bigger the pack, the cheaper the tablet
A$61.44A$51.19
A$1.71 per tablet

In brief

Imipramine hydrochloride, a tricyclic antidepressant, carries the brand name Tofranil on the Australian market. Healthdirect lists two uses for Tofranil: major depression, and bed-wetting at night in children aged 5 or older when an organic cause has been excluded.

A tricyclic antidepressant with a second use in childhood enuresis

Imipramine hydrochloride belongs to the tricyclic group of antidepressants, as the Tofranil CMI on myDr explains. The healthdirect page for Tofranil names major depression as one use and night-time bed-wetting in children from 5 years of age as the other, provided organic causes have been ruled out.
This listing shows imipramine 25 mg, 50 mg and 75 mg. It does not name the manufacturer of the product supplied, so check the label on the pack you receive and confirm with your prescriber or pharmacist that it matches your prescription.

Imipramine 50 mg: 30 units or 90 units

Compare packs of the same strength. These examples are for 50 mg and are calculated from the listed prices at the shop’s Australian-dollar rate on 9 October 2026, before delivery or other checkout charges.
Strength Pack size Pack price Price per unit
50 mg 30 A$64.65 A$2.15
50 mg 90 A$135.06 A$1.50
The 90-unit pack works out roughly 30.4% cheaper per unit than the 30-unit pack.
A lower price per unit means a larger upfront payment. Choose only the quantity and strength appropriate to your prescription, and check the expiry date. Prices can change, so confirm the current pack price before ordering.

Tofranil registration in Australia covers 10 mg and 25 mg tablets

Amdipharm Mercury (Australia) Pty Ltd supplies Tofranil here, and healthdirect records it as sugar-coated tablets in two strengths, 10 mg and 25 mg. It is a Schedule 4 Prescription Only Medicine, and healthdirect listed it as subsidised under the PBS as of 1 October 2026. In other words, the 50 mg and 75 mg choices on this page have no Australian registration under the Tofranil name.

Tofranil and a wait of up to 4 to 6 weeks for improvement

The Tofranil CMI states that a noticeable improvement may take up to 4 to 6 weeks to arrive.

Reasons the CMI gives for not taking Tofranil at all

Tofranil is not to be used by anyone allergic to imipramine or to another tricyclic antidepressant, by people currently on an MAO inhibitor, or during recovery from a recent heart attack. After an MAO inhibitor is stopped, two weeks need to pass before imipramine can be started.

Mood, eyes, bladder, heart and daily activities: Tofranil cautions

The CMI warns that suicidal thoughts may occur, with younger people at particular risk, and asks that a doctor be contacted straight away if they do. Do not stop the medicine without first speaking with your doctor. Extra care is needed for people with glaucoma, trouble passing urine, seizures or a heart condition. Alcohol should be avoided, and you should not drive until you have found out how Tofranil affects you. Healthdirect adds that people over 65 face particular risks worth discussing with a doctor, and that advice from a doctor or pharmacist is needed in pregnancy.

Sleepiness, constipation and other Tofranil side effects, plus interactions

Side effects often reported with Tofranil include drowsiness, dizziness, dry mouth, constipation, weight gain, sexual dysfunction and blurred vision. Listed among the serious effects are allergic reactions, a heartbeat that becomes irregular, severe confusion, and movements a person cannot control. Medicines and products the CMI flags for possible interactions are MAO inhibitors, blood pressure medicines, SSRIs, anticonvulsants, warfarin, certain cold remedies and nicotine products.

Storing Tofranil below 30 °C in a dry place

According to healthdirect, Tofranil should be stored below 30 °C and kept away from moisture. Follow the storage directions on the pack you receive.

Delivery across Australia

Standard delivery: 14–22 days. Express tracked delivery: 7–14 days, with the tracking number sent by email. These are estimated delivery times, not guaranteed arrival dates.

Australian cities and delivery information

The Australian delivery options above apply to the destinations below. A city listing does not indicate a physical pharmacy branch or local stock.
City State or territory
Sydney New South Wales
Melbourne Victoria
Brisbane Queensland
Perth Western Australia
Adelaide South Australia
Hobart Tasmania
Gold Coast Queensland
Canberra Australian Capital Territory
Cairns Queensland
Central Coast New South Wales
Townsville Queensland
Darwin Northern Territory
Newcastle New South Wales
Geelong Victoria
Gladstone Queensland
Port Macquarie New South Wales
Bathurst New South Wales
Forbes New South Wales
Geraldton Western Australia
Goulburn New South Wales

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